Generic Name: Atropine Sulphate
Volume: 1ml and 10ml
Therapeutic category: Anticholinergics
Description: EVAPIN is clear, colorless, almost colorless to pale yellow solution. It contains 0.6mg/ml of Atropine Sulphate and it belongs to a group of medicines called Anticholinergic.
How EVAPIN works?
EVAPIN inhibits the muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites including smooth muscle, secretory glands and CNS sites. Small doses of EVAPIN inhibit salivary and bronchial secretions and sweating; moderate doses dilate the pupil, inhibit accommodation and increase the heart rate (vagolytic effect); larger doses will decrease motility of the GI and urinary tracts; very large doses will inhibit gastric acid secretion.
EVAPIN Injection is indicated for temporary blockade of severe or life-threatening muscarinic effects, e.g., as an antisialagogue, an antivagal agent, an antidote for organophosphorus or muscarinic mushroom poisoning, and to treat bradyasystolic cardiac arrest.
Dosage and administration:
Adults: 400 to 600 mcg every four to six hours.
Children: 1 year: 120 mcg
2 to 4 years: 180mcg
- Greater than 4 years: The dose may be increased by 20 mcg for each year of age to a maximum of 300 mcg.
N.B.: The complete EVAPIN dose in man is usually believed to be in the order of 2mg intravenously.
Administration: EVAPIN Injection may be given subcutaneously, intramuscularly or intravenously.
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